The Effect of Repeated Botulinum Toxin A Therapy Combined with Intensive Rehabilitation on Lower Limb Spasticity in Post-Stroke Patients

The Effect of Repeated Botulinum Toxin A Therapy Combined with Intensive Rehabilitation on Lower Limb Spasticity in Post-Stroke Patients

Blog Article

Objectives: This study is a Cutlery retrospective investigation of the effects of repetitive botulinum toxin A therapy (BoNT-A) and intensive rehabilitation (IR) on lower limb spasticity in post-stroke patients.Methods: Thirty-five post-stroke patients was included in this study and received BoNT-A for the first time.A 12-day inpatient protocol was with 4 cycles of the treatment protocol.

The severity of spasticity, motor function and brace status were evaluated.Results: The modified Ashworth Scale (MAS) score of ankle dorsiflexors, range of motion, walking speed and balancing ability were significantly improved after cycle 1.The improvement of spasticity B-12 Methylcobalamin and motor function was persistent through cycles 2–4.

One-third of brace users were able to discontinue the use of a brace.All of these brace users showed a forward gait pattern prior to therapy.Conclusions: Repeated BoNT-A combined with IR improved lower limb spasticity in post-stroke patients.

Our results suggest that patients who show the forward gait pattern prior to therapy may be able to discontinue the use of their brace after therapy.